Research

Targeted protein degradation through Bifunctional Molecules

Bifunctional Molecules

Bifunctional molecules that target extracellular proteins for endocytosis and subsequent lysosomal degradation, termed as molecular degraders of extracellular proteins (MoDEs), or LYTACs.

Molecular degraders of extracellular proteins
(MoDEs)

Spiegel Lab and others extend the field of TPD through bifunctional molecules that target extracellular proteins for endocytosis and subsequent lysosomal degradation, termed as Molecular Degraders of Extracellular proteins (MoDEs), or LYTACs.

Research

Targeted protein degradation through Bifunctional Molecules

Bifunctional Molecules

Molecular degraders of extracellular proteins
(MoDEs)

Spiegel Lab and others extend the field of TPD through bifunctional molecules that target extracellular proteins for endocytosis and subsequent lysosomal degradation, termed as Molecular Degraders of Extracellular proteins (MoDEs), or LYTACs.

Antibody-Recruiting Molecules
(ARMs)

Stay Updated with Our Research

Research

Targeted protein degradation through Bifunctional Molecules

Bifunctional Molecules

Molecular degraders of extracellular proteins (MoDEs) Spiegel Lab and others extend the field of TPD through bifunctional molecules that target extracellular proteins for endocytosis and subsequent lysosomal degradation, termed as Molecular Degraders of Extracellular proteins (MoDEs), or LYTACs.

Antibody-Recruiting Molecules (ARMs)

Stay Updated with Our Research

Molecular degraders of extracellular proteins
(MoDEs)

Spiegel Lab and others extend the field of TPD through bifunctional molecules that target extracellular proteins for endocytosis and subsequent lysosomal degradation, termed as Molecular Degraders of Extracellular proteins (MoDEs), or LYTACs.

Antibody-Recruiting Molecules
(ARMs)